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Wednesday, March 1, 2017

Albuterol Inhalation

Generic Name: albuterol inhalation (al BYOO ter all)
Brand Names: ProAir HFA, ProAir RespiClick, Proventil HFA, Ventolin HFA

What is albuterol inhalation?

Albuterol is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs.

Albuterol inhalation is used to treat or prevent bronchospasm in people with reversible obstructive airway disease. It is also used to prevent exercise-induced bronchospasm.

Albuterol inhalation is for use in adults and children who are at least 4 years old.

Important information
It is important to keep albuterol on hand at all times. Get your prescription refilled before you run out of medicine completely. Keep using all of your other medications as prescribed by your doctor.

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Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing attacks. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor. An increased need for medication could be an early sign of a serious asthma attack.

An overdose of albuterol can be fatal. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Before taking this medicine
You should not use this medicine if you are allergic to albuterol. You should not use ProAir RespiClick if you are allergic to milk proteins.

To make sure albuterol inhalation is safe for you, tell your doctor if you have:

heart disease, high blood pressure, congestive heart failure;
a heart rhythm disorder;
a seizure disorder such as epilepsy;
diabetes;
overactive thyroid; or
low levels of potassium in your blood.
It is not known whether albuterol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether albuterol inhalation passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Albuterol inhalation is not approved for use by anyone younger than 4 years old.


How should I use albuterol inhalation?
Use albuterol inhalation exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use albuterol inhalation in larger or smaller amounts or for longer than recommended.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

You may need to prime your albuterol inhaler device before the first use. Your medicine comes with directions for priming if needed.

You may also need to shake your albuterol device just before each use.

Follow all medication instructions very carefully.

Do not allow a young child to use albuterol inhalation without help from an adult.

The usual dose of albuterol inhalation is 2 inhalations every 4 to 6 hours. To prevent exercise-induced bronchospasm, use 2 inhalations 15 to 30 minutes before you exercise. The effects of albuterol inhalation should last about 4 to 6 hours.

Seek medical attention if you think your asthma medications are not working as well. An increased need for medication could be an early sign of a serious asthma attack.

Use the dose counter on your albuterol inhaler device and get your prescription refilled before you run out of medicine completely. Always use the new inhaler device provided with your refill. Do not float a medicine canister in water to see if it is empty.

Follow all product instructions on how to clean your albuterol inhaler device and mouthpiece. Do not try to clean or take apart the ProAir RespiClick inhaler device.

Asthma is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

Store at room temperature away from moisture, heat, or cold temperatures.

Keep the albuterol canister away from open flame or high heat, such as in a car on a hot day. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.

See also: Dosage Information (in more detail)

What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of albuterol can be fatal.

Overdose symptoms may include dry mouth, tremors, chest pain, fast heartbeats, nausea, general ill feeling, seizure (convulsions), feeling light-headed or fainting.

What should I avoid while using albuterol inhalation?
Rinse with water if this medicine gets in your eyes.


Albuterol inhalation side effects
Get emergency medical help if you have signs of an allergic reaction to albuterol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

wheezing, choking, or other breathing problems after using this medicine;
chest pain, fast heart rate, pounding heartbeats or fluttering in your chest;
pain or burning when you urinate;
high blood sugar - increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or
low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, extreme thirst, increased urination, numbness or tingling, muscle weakness or limp feeling.
Common albuterol side effects may include:

back pain, body aches;
headache, dizziness;
feeling nervous;
nausea, diarrhea, upset stomach; or
sore throat, sinus pain, stuffy runny nose.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect albuterol inhalation?
Tell your doctor about all your current medicines and any you start or stop using, especially:

any other inhaled medicines or bronchodilators;
digoxin;
a diuretic or "water pill";
an antidepressant - amitriptyline, desipramine, imipramine, doxepin, nortriptyline, and others;
a beta blocker - atenolol, carvedilol, labetalol, metoprolol, propranolol, sotalol, and others; or
an MAO inhibitor - isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
This list is not complete. Other drugs may interact with albuterol inhalation, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Adderall


Generic Name: amphetamine and dextroamphetamine (am FET a meen and DEX troe am FET a meen)
Brand Names: Adderall, Adderall XR


What is Adderall?

Adderall contains a combination of amphetamine and dextroamphetamine. Amphetamine and dextroamphetamine are central nervous system stimulants that affect chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Adderall is used to treat narcolepsy and attention deficit hyperactivity disorder (ADHD).

Adderall may also be used for purposes not listed in this medication guide.

Important information
You should not use Adderall if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, or a history of drug or alcohol addiction.

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Do not use Adderall if you have taken an MAO inhibitor in the past 14 days, including isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Adderall may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction.

Using this medicine improperly can cause death or serious side effects on the heart.

Before taking this medicine
Do not use Adderall if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use Adderall if you are allergic to any stimulant medicine, or if you have:

moderate to severe high blood pressure;
heart disease or coronary artery disease (hardened arteries);
overactive thyroid;
glaucoma;
severe anxiety, tension, or agitation (stimulant medicine can make these symptoms worse); or
a history of drug or alcohol addiction.
Some stimulants have caused sudden death in certain people. Tell your doctor if you have:

heart problems or a congenital heart defect;
high blood pressure; or
a family history of heart disease or sudden death.
To make sure Adderall is safe for you, tell your doctor if you or anyone in your family has ever had:

depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions;
motor tics (muscle twitches) or Tourette's syndrome;
seizures or epilepsy;
an abnormal brain wave test (EEG); or
blood circulation problems in the hands or feet.
It is not known whether Adderall will harm an unborn baby. However, taking the medicine during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Amphetamine and dextroamphetamine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

Adderall is not approved for use by anyone younger than 6 years old.


How should I take Adderall?
Take Adderall exactly as prescribed by your doctor. Using this medicine improperly can cause death or serious side effects on the heart.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Adderall may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Selling or giving away this medicine is against the law.

You may take this medicine with or without food. It is best to take Adderall first thing in the morning.

Do not crush, chew, break, or open an Adderall XR extended-release capsule. Swallow it whole.

To make swallowing easier, you may open the capsule and sprinkle the medicine into a spoonful of applesauce. Swallow right away without chewing. Do not save the mixture for later use.

While using Adderall, your doctor will need to check your progress at regular visits. Your heart rate, blood pressure, height and weight may also need to be checked often.

Adderall can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using this medicine.

Store at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Adderall is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

See also: Dosage Information (in more detail)

What happens if I miss a dose?
Take the missed dose as soon as you remember, but not late in the day or you could have trouble sleeping. Skip the missed dose if it is almost evening. Do not take extra medicine to make up the missed dose.

Adderall dosing information
Usual Adult Dose of Adderall for Narcolepsy:

Tablets:
Initial Dose: 10 mg per day orally upon awakening.
Maintenance Dose: The daily dosage may be increased in increments of 10 mg at weekly intervals, up to 60 mg per day in 2 to 3 divided doses. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced.

Usual Adult Dose of Adderall for Attention Deficit Disorder:

Extended Release Capsules:
Initial Dose: In adults with ADHD who are either starting treatment for the first time or switching from another medication, the recommended dose is 20 mg/day.

Usual Pediatric Dose of Adderall for Narcolepsy:

Tablets:
<6 years: Not recommended.

6 years to 12 years:
Initial Dose: 5 mg per day orally upon awakening.
Maintenance Dose: The daily dose may be raised in increments of 5 mg at weekly intervals until optimal response is obtained, up to a maximum of 60 mg/day. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced. Narcolepsy seldom occurs in children under 12 years of age; however, when it does, this drug may be used.

>=12 years:
Initial Dose: 10 mg per day orally upon awakening.
Maintenance Dose: The daily dosage may be raised in increments of 10 mg at weekly intervals until optimal response is obtained, up to a maximum of 60 mg/day. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced.

Usual Pediatric Dose of Adderall for Attention Deficit Disorder:

Tablets:
<3 years: Not recommended.

3 to 5 years:
Initial Dose: 2.5 mg once a day orally upon awakening.
Maintenance Dose: The daily dosage may be raised in increments of 2.5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day in 2 to 3 divided doses. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.

>= 6 years:
Initial Dose: 5 mg once or twice a day orally upon awakening.
Maintenance Dose: The daily dosage may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day in 2 to 3 divided doses. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.

Extended Release Capsules:
<6 years: Not recommended.

6 to 12 years:
Initial Dose: 5 mg to 10 mg once a day orally upon awakening.
Maintenance Dose: The daily dosage may be raised in increments of 5 mg to 10 mg at weekly intervals.
Maximum Dose: 30 mg once daily upon awakening.

13 to 17 years:
Initial Dose: 10 mg once a day orally upon awakening.
Maintenance Dose: The daily dosage may be increased to 20 mg once a day orally upon awakening after one week if ADHD symptoms are not adequately controlled.
Maximum Dose: 20 mg once daily upon awakening.

Where possible, drug administration should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy.

Drug treatment is not indicated in all cases of Attention Deficit Disorder with Hyperactivity and should be considered only in light of the complete history and evaluation of the child. The decision to prescribe amphetamines should depend on the physician's assessment of the chronicity and severity of the child's symptoms and their appropriateness for his/her age. Prescription should not depend solely on the presence of one or more of the behavioral characteristics. When these symptoms are associated with acute stress reactions, treatment with amphetamines is usually not indicated.

What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amphetamine and dextroamphetamine could be fatal.

Overdose symptoms may include restlessness, tremor, muscle twitches, rapid breathing, confusion, hallucinations, panic, aggressiveness, muscle pain or weakness, and dark colored urine. These symptoms may be followed by depression and tiredness. Other overdose symptoms include nausea, vomiting, diarrhea, stomach pain, uneven heartbeats, feeling light-headed, fainting, seizure (convulsions), or coma.

What should I avoid while taking Adderall?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid drinking fruit juices or taking vitamin C at the same time you take Adderall. These can make your body absorb less of the medicine.


Adderall side effects
Get emergency medical help if you have signs of an allergic reaction to Adderall: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Adderall can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Stop using this medicine and call your doctor at once if you have:

chest pain, trouble breathing, feeling like you might pass out;
hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia;
a seizure (convulsions);
numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes;
muscle twitches (tics);
changes in your vision; or
unexplained muscle pain, tenderness, or weakness (especially if you also have fever, unusual tiredness, and dark colored urine).
Common Adderall side effects may include:

stomach pain, loss of appetite;
weight loss;
mood changes, feeling nervous;
fast heart rate;
headache, dizziness;
sleep problems (insomnia); or
dry mouth.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Adderall?
Many drugs can interact with amphetamine and dextroamphetamine. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

an antacid or other stomach acid reducer, such as Nexium, Pepcid, Prilosec, Protonix, Zantac, and others;
an antidepressant;
blood pressure medication;
a blood thinner such as warfarin (Coumadin, Jantoven);
a cold or allergy medicine that contains a decongestant such as pseudoephedrine or phenylephrine;
lithium;
medicine to treat mental illness;
narcotic pain medicine; or
seizure medicine.
This list is not complete and many other drugs can interact with amphetamine and dextroamphetamine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Acyclovir

Generic Name: acyclovir (oral) (a SYE klo veer)
Brand Names: Sitavig, Zovirax


What is acyclovir?

Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. It will not cure herpes, but it can lessen the symptoms of the infection.

Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chicken pox.

Acyclovir may also be used for purposes not listed in this medication guide.

Important information
Take acyclovir for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated.

Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

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Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Before taking this medicine
You should not take this medicine if you are allergic to acyclovir or valacyclovir (Valtrex). You should not take acyclovir buccal tablets (Sitavig) if you are allergic to milk proteins.

To make sure acyclovir is safe for you, tell your doctor if you have:

kidney disease; or
a weak immune system (caused by disease or by using certain medicine).
FDA pregnancy category B. Acyclovir is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

See also: Pregnancy and breastfeeding warnings (in more detail)

Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection.

Acyclovir passes into breast milk and may harm a nursing infant. Do not take this medication without telling your doctor if you are breast-feeding a baby.

Do not give an acyclovir buccal tablet to a young child or choking could occur.


How should I take acyclovir?
Take acyclovir exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

To take the acyclovir buccal tablet (Sitavig):

Keep the tablet in its blister pack until you are ready to take it. Use a dry finger to remove the tablet.
Do not chew or swallow a buccal tablet. Place the flat side of the tablet against your upper gum, behind your lip and above your canine tooth. Place the tablet on the same side of the mouth as your cold sore.
Close your mouth and gently press on the outside of your lip over the tablet, holding it in place for 30 seconds. Avoid touching or pressing on the tablet once it is in place.
Allow the tablet to dissolve in your mouth throughout the day. You may eat and drink normally while the buccal tablet is in place.
During the first 6 hours of wearing time: If the tablet falls off or does not stick well, you may replace it with a new tablet. If you accidentally swallow the tablet, drink a glass of water and put a new tablet in place.
Tell your doctor if you have any changes in weight. Acyclovir doses are based on weight (especially in children and teenagers), and any changes may affect the dose.

Drink plenty of water while you are taking acyclovir to keep your kidneys working properly.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely treated. Acyclovir will not treat a viral infection such as the flu or a common cold.

Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

Store at room temperature away from moisture and heat.

See also: Dosage Information (in more detail)

What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include agitation, seizure (convulsions), or loss of consciousness.

What should I avoid while taking acyclovir?
Avoid brushing your teeth, chewing gum, or wearing an upper denture while you have a buccal tablet in your mouth. You may rinse your mouth gently. Drink plenty of liquids to prevent dry mouth.

Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.

Taking this medicine will not prevent you from passing genital herpes to your sexual partner. Avoid sexual intercourse while you have active lesions or the first symptoms of an outbreak. Genital herpes may still be contagious through "viral shedding" from your skin, even if you have no symptoms.


Acyclovir side effects
Get emergency medical help if you have any of these signs of an allergic reaction to acyclovir: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

easy bruising or bleeding, purple or red pinpoint spots under your skin; or
signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath.
Common acyclovir side effects may include:

nausea, vomiting;
diarrhea;
general ill feeling;
headache; or
mouth pain while using an acyclovir buccal tablet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect acyclovir?
Acyclovir can harm your kidneys. This effect is increased when you also use certain other medicines, including: probenecid, antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, injectable osteoporosis medication, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve).

Other drugs may interact with acyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Acetaminophen



Generic Name: acetaminophen (oral) (a SEET a MIN oh fen)
Brand Names: Actamin, Apra, Mapap, Q-Pap, Tactinal, Tempra, Tycolene, Tylenol, Vitapap


What is acetaminophen?


Acetaminophen is a pain reliever and a fever reducer.

Acetaminophen is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.

Acetaminophen may also be used for purposes not listed in this medication guide.

Important information
You should not use acetaminophen if you have severe liver disease.

There are many brands and forms of acetaminophen available and not all brands are listed on this leaflet.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).
Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take this medicine. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

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Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

In rare cases, acetaminophen may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Before taking this medicine
You should not take acetaminophen if you are allergic to it, or if you have severe liver disease.

Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take acetaminophen.

Your doctor will determine whether acetaminophen is safe for you to use during pregnancy. Do not use this medicine without the advice of your doctor if you are pregnant.

Acetaminophen can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to a child younger than 2 years old without the advice of a doctor.


How should I take acetaminophen?
Use acetaminophen exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

If you are treating a child, use a pediatric form of acetaminophen. Use only the special dose-measuring dropper or oral syringe that comes with the specific pediatric form you are using. Carefully follow the dosing directions on the medicine label.

Acetaminophen made for infants is available in two different dose concentrations, and each concentration comes with its own medicine dropper or oral syringe. These dosing devices are not equal between the different concentrations. Using the wrong device may cause you to give your child an overdose of acetaminophen. Never mix and match dosing devices between infant formulations of acetaminophen.

You may need to shake the liquid before each use. Follow the directions on the medicine label.

The chewable tablet must be chewed thoroughly before you swallow it.

Make sure your hands are dry when handling the acetaminophen disintegrating tablet. Place the tablet on your tongue. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

To use the acetaminophen effervescent granules, dissolve one packet of the granules in at least 4 ounces of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Stop taking acetaminophen and call your doctor if:

you still have a fever after 3 days of use;
you still have pain after 7 days of use (or 5 days if treating a child);
you have a skin rash, ongoing headache, or any redness or swelling; or
if your symptoms get worse, or if you have any new symptoms.
This medication can cause unusual results with certain lab tests for glucose (sugar) in the urine. Tell any doctor who treats you that you are using acetaminophen.

Store at room temperature away from heat and moisture.

See also: Dosage Information (in more detail)

What happens if I miss a dose?
Since acetaminophen is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

What should I avoid?
Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.


Acetaminophen side effects
Get emergency medical help if you have any signs of an allergic reaction to acetaminophen: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Stop taking this medication and call your doctor at once if you have:

nausea, upper stomach pain, itching, loss of appetite;
dark urine, clay-colored stools; or
jaundice (yellowing of the skin or eyes).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Acetaminophen dosing information
Usual Adult Dose for Fever:

IV:
Adults and adolescents weighing 50 kg and over: 1000 mg every 6 hours or 650 mg every 4 hours, with a maximum single dose of 1000 mg, a minimum dosing interval of 4 hours, and a maximum daily dose of acetaminophen of 4000 mg per day.
Adults and adolescents weighing under 50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours, with a maximum single dose of 15 mg/kg, a minimum dosing interval of 4 hours, and a maximum daily dose of acetaminophen of 75 mg/kg per day.

Orally or Rectally:
General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours

No dose adjustment is required when converting between oral and IV acetaminophen dosing in adults and adolescents. The maximum daily dose of acetaminophen is based on all routes of administration
(i.e. intravenous, oral, and rectal) and all products containing acetaminophen.

Usual Adult Dose for Pain:

IV:
Adults and adolescents weighing 50 kg and over: 1000 mg every 6 hours or 650 mg every 4 hours, with a maximum single dose of 1000 mg, a minimum dosing interval of 4 hours, and a maximum daily dose of acetaminophen of 4000 mg per day.
Adults and adolescents weighing under 50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours, with a maximum single dose of 15 mg/kg, a minimum dosing interval of 4 hours, and a maximum daily dose of acetaminophen of 75 mg/kg per day.

Orally or Rectally:
General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours

No dose adjustment is required when converting between oral and IV acetaminophen dosing in adults and adolescents. The maximum daily dose of acetaminophen is based on all routes of administration
(i.e. intravenous, oral, and rectal) and all products containing acetaminophen.

Usual Pediatric Dose for Fever:

Preterm neonates 28 to 32 weeks:
IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 12 hours
Oral: 10 to 12 mg/kg/dose every 6 to 8 hours
Maximum oral daily dose: 40 mg/kg/day
Rectal: 20 mg/kg/dose every 12 hours
Maximum rectal daily dose: 40 mg/kg/day

Preterm neonates 32 to 37 weeks and term neonates less than 10 days:
IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 6 hours
Oral: 10 to 15 mg/kg/dose every 6 hours
Maximum daily dose: 60 mg/kg/day
Rectal: Loading dose: 30 mg/kg; then 15 mg/kg/dose every 8 hours
Maximum daily dose: 60 mg/kg/day

Term neonates greater than or equal to 10 days:
IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 6 hours
Oral: 10 to 15 mg/kg/dose every 4 to 6 hours
Maximum daily dose: 90 mg/kg/day
Rectal: Loading dose: 30 mg/kg; then 20 mg/kg/dose every 6 to 8 hours
Maximum daily dose: 90 mg/kg/day

Infants and Children:
IV: Less than 2 years: 7.5 to 15 mg/kg/dose every 6 hours
Maximum daily dose: 60 mg/kg/day
IV: 2 to 12 years: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours
Maximum single dose 15 mg

Abilify


Generic Name: aripiprazole (AR i PIP ra zole)
Brand Names: Abilify, Abilify Discmelt


What is Abilify?
Abilify (aripiprazole is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Abilify is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar I disorder (manic depression). It is not known if aripiprazole is safe or effective in children younger than 13 with schizophrenia, or children younger than 10 with bipolar disorder.

Abilify is also used together with other medicines to treat major depressive disorder in adults.

Abilify is also used in children 6 years or older who have Tourette's disorder, or symptoms of autistic disorder (irritability, aggression, mood swings, temper tantrums, and self-injury).

Important information
Abilify is not approved for use in psychotic conditions related to dementia. Abilify may increase the risk of death in older adults with dementia-related conditions.

Some young people have thoughts about suicide when taking medicine for a major depressive disorder and other psychiatric disorders. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

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Some young people have thoughts about suicide when taking medicine for a major depressive disorder and other psychiatric disorders. Your doctor will need to check your progress at regular visits while you are using Abilify. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Stop using Abilify and call your doctor at once if you have the following symptoms: fever with stiff muscles and rapid heart rate; uncontrolled muscle movements; symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance.

Before taking this medicine
You should not take Abilify if you are allergic to aripiprazole.

Abilify is not approved for use in psychotic conditions related to dementia. Aripiprazole may increase the risk of death in older adults with dementia-related conditions.

To make sure Abilify is safe for you, tell your doctor if you have:

liver or kidney disease;
heart disease, high or low blood pressure, heart rhythm problems;
high cholesterol or triglycerides (a type of fat in the blood);
a history of low white blood cell (WBC) counts;
a history of heart attack or stroke;
seizures or epilepsy;
trouble swallowing;
a personal or family history of diabetes; or
a history of obsessive-compulsive disorder, impulse-control disorder, or addictive behaviors.
Some young people have thoughts about suicide when taking medicine for a major depressive disorder and other psychiatric disorders. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

The liquid form (oral solution) of this medication may contain up to 15 grams of sugar per dose. Before taking Abilify oral solution, tell your doctor if you have diabetes.

Abilify may cause you to have high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis while you are taking this medicine.

The orally disintegrating tablet form of this medication may contain over 3 milligrams of phenylalanine per tablet. Before taking Abilify Discmelt, tell your doctor if you have phenylketonuria.

Taking antipsychotic medicine in the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant, do not stop taking Abilify without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of aripiprazole on the baby.

Aripiprazole can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.


How should I take Abilify?
Take Abilify exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not take Abilify for longer than 6 weeks unless your doctor has told you to.

Abilify can be taken with or without food.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

To take the orally disintegrating tablet (Discmelt):

Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil. Do not push a tablet through the foil or you may damage the tablet.
Use dry hands to remove the tablet and place it in your mouth.
Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. If desired, you may drink liquid to help swallow the dissolved tablet.
Use Abilify regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

You should not stop using Abilify suddenly. Stopping suddenly may make your condition worse.

Your doctor will need to check your progress while you are using this medicine.

Store at room temperature away from moisture and heat. Abilify liquid may be used for up to 6 months after opening, but not after the expiration date on the medicine label.

See also: Dosage Information (in more detail)

What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), trouble breathing, or fainting.

What should I avoid while taking Abilify?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. Dangerous side effects could occur.

Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Abilify.


Abilify side effects
Get emergency medical help if you have signs of an allergic reaction to Abilify: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

severe agitation, distress, or restless feeling;
twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
mask-like appearance of the face, trouble swallowing, problems with speech;
seizure (convulsions);
thoughts about suicide or hurting yourself;
severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
low blood cell counts--sudden weakness or ill feeling, fever, chills, sore throat, swollen gums, painful mouth sores, red or swollen gums, skin sores, cold or flu symptoms, cough, trouble breathing; or
high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, weight loss.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.

Common Abilify side effects may include:

weight gain;
blurred vision;
nausea, vomiting, changes in appetite, constipation;
drooling;
headache, dizziness, drowsiness, feeling tired;
anxiety, feeling restless;
sleep problems (insomnia); or
cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Abilify?
Taking Abilify with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Many other drugs can interact with aripiprazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Abilify.