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Dyazide
Generic Name: hydrochlorothiazide and triamterene (HYE dro klor oh THY a zide and trye AM ter een)
Brand Names: Dyazide, Maxzide, Maxzide-25
Brand Names: Dyazide, Maxzide, Maxzide-25
What is Dyazide?
Dyazide contains a combination of hydrochlorothiazide and triamterene. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Triamterene is a potassium-sparing diuretic that also prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.
Dyazide is used to treat fluid retention (edema) and high blood pressure (hypertension).
Dyazide may also be used for other purposes not listed in this medication guide.
Important information
You should not use Dyazide if you are allergic to hydrochlorothiazide or triamterene, or if you have kidney disease, urination problems, high levels of potassium in your blood, or if you are taking other diuretics similar to triamterene. Do not use potassium supplements unless your doctor has told you to.
Before using Dyazide, tell your doctor if you have heart or liver disease, glaucoma, diabetes, a breathing disorder, gout, lupus, kidney stones, a pancreas disorder, or an allergy to sulfa drugs or penicillin.
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Drinking alcohol can further lower your blood pressure and may increase certain side effects of Dyazide.
Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.
Do not use potassium supplements, salt substitutes, or low-sodium milk while you are taking Dyazide, unless your doctor has told you to.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
If you are being treated for high blood pressure, keep using Dyazide even if you feel fine. High blood pressure often has no symptoms.
Before taking this medicine
You should not use Dyazide if you are allergic to hydrochlorothiazide (HCTZ, HydroDiuril, Lotensin HCT, Prinzide, Zestoretic, Ziac, and others) or triamterene (Dyrenium), or if you have:
kidney disease or are unable to urinate;
high potassium levels (hyperkalemia);
if you are taking diuretics similar to triamterene, such as amiloride (Midamor, Moduretic), spironolactone (Aldactone, Aldactazide); or
if you are taking potassium supplements (unless your doctor tells you to).
To make sure you can safely take Dyazide, tell your doctor if you have any of these other conditions:
diabetes;
heart disease;
cirrhosis or other liver disease;
glaucoma;
a breathing disorder;
gout;
lupus;
a history of kidney stones;
a pancreas disorder; or
an allergy to sulfa drugs or penicillin.
FDA pregnancy category C. It is not known whether Dyazide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using Dyazide. Hydrochlorothiazide and triamterene can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking Dyazide.
See also: Pregnancy and breastfeeding warnings (in more detail)
How should I take Dyazide?
Take Dyazide exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
You will need regular medical tests to be sure Dyazide is not causing harmful effects. Visit your doctor regularly.
If you need surgery or medical tests, tell the doctor ahead of time that you are taking medication that contains hydrochlorothiazide. You may need to stop using Dyazide for a short time.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store Dyazide at room temperature away from moisture, heat, and light.
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include increased urination, nausea, vomiting, weakness, fever, warmth or flushing in your face, or muscle spasms.
What should I avoid?
Drinking alcohol can further lower your blood pressure and may increase certain side effects of Dyazide.
Avoid a diet high in salt. Too much salt will cause your body to retain water and can make this medication less effective.
Do not use potassium supplements, salt substitutes, or low-sodium milk while you are taking Dyazide, unless your doctor has told you to. Dyazide may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
Dyazide side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Dyazide: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Dyazide and call your doctor at once if you have a serious side effect such as:
eye pain, vision problems;
slow, fast, or uneven heartbeat;
feeling like you might pass out;
swelling or rapid weight gain;
urinating less than usual or not at all;
headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops;
low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
high potassium (irregular heart rate, weak pulse, muscle weakness, tingly feeling);
severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
patchy skin color, red spots, or a butterfly-shaped skin rash over your cheeks and nose (worsens in sunlight);
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
jaundice (yellowing of the skin or eyes).
Less serious Dyazide side effects may include:
mild nausea, diarrhea, constipation;
dizziness, headache;
blurred vision;
dry mouth;
skin rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs can affect Dyazide?
Before using Dyazide, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Dyazide.
Tell your doctor about all other medicines you use, especially:
lithium (Eskalith, LithoBid);
amphotericin B (Amphotec, AmBisome, Abelcet);
methenamine (Hiprex, Mandelamine, Urex);
gout medication such as allopurinol (Zyloprim), colchicine (Colcrys), or probenecid (Benemid);
steroid medication (prednisone and others);
a blood thinner such as warfarin (Coumadin, Jantoven);
insulin or oral diabetes medicine;
laxatives;
an ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others; or
indomethacin (Indocin) or other NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.
This list is not complete and other drugs may interact with Dyazide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Dulera Inhaler
Generic Name: formoterol and mometasone (for MOE ter ol and moe MET a sone)
Brand Names: Dulera
Brand Names: Dulera
What is Dulera?
Dulera inhalers contain a combination of formoterol and mometasone. Formoterol is a long-acting bronchodilator that relaxes muscles in the airways to improve breathing. Mometasone is a steroid. It prevents the release of substances in the body that cause inflammation.
Dulera inhalers are used as a maintenance treatment for asthma in adults and children who are at least 12 years old. Dulera is not for use in treating an asthma or bronchospasm attack.
Dulera may also be used for purposes not listed in this medication guide.
Important information
Formoterol may increase the risk of asthma-related death. Use only the prescribed dose of Dulera, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Talk with your doctor about your individual risks and benefits of using a Dulera inhaler.
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Dulera will not work fast enough to treat an asthma attack. Use only a fast acting inhalation medicine for an asthma attack. Tell your doctor if it seems like your asthma medications don't work as well.
Before using Dulera
You should not use Dulera if you are allergic to formoterol (Foradil, Perforomist, Symbicort) or mometasone (Asmanex).
To make sure Dulera is safe for you, tell your doctor if you have:
an active infection of any kind;
heart disease;
liver disease;
low bone mineral density;
glaucoma or cataracts;
epilepsy or other seizure disorder;
diabetes;
pheochromocytoma (tumor of the adrenal gland);
a thyroid disorder; or
a history of aneurysm (a weakened or damaged blood vessel that could tear and cause severe bleeding).
It is not known whether Dulera will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether formoterol and mometasone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Mometasone can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using Dulera.
Do not give Dulera to a child younger than 12 years old without the advice of a doctor.
Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis. Talk with your doctor about your risk of osteoporosis.
How should I use Dulera?
Dulera comes with patient instructions for safe and effective use, and directions for priming the inhaler device. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Formoterol may increase the risk of asthma-related death. Use only the prescribed dose of Dulera, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Talk with your doctor about your individual risks and benefits of using Dulera.
Dulera will not work fast enough to treat an asthma attack. Use only a fast acting inhalation medicine for an asthma attack.
Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack.
Shake the Dulera inhaler canister well before each use. Remove the cap from the mouthpiece before placing the inhaler in your mouth.
To reduce the chance of developing a yeast infection in your mouth, rinse with water after using the inhaler. Do not swallow.
It may take up to 1 week before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 1 week of treatment.
If you need surgery, tell the surgeon ahead of time that you are using Dulera.
If you also use a steroid medication, you should not stop using Dulera suddenly. Follow your doctor's instructions about tapering your dose.
Asthma is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.
Store Dulera at room temperature away from moisture and heat.
Store the 60-inhalation canister upright with the mouthpiece down, or on its side. Keep the medicine canister away from open flame or high heat, such as in a car on a hot day. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.
Do not try to clean or take apart the Aerolizer device. Throw it away when your capsules run out. Always use the new device provided with the medication when you get your prescription refilled.
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Dulera dosing information
Usual Adult Dose of Dulera for Asthma - Maintenance:
The recommended starting dosages for formoterol-mometasone treatment are based on prior asthma therapy.
For previous therapy of medium dose inhaled corticosteroids: 5 mcg-100 mcg 2 inhalations twice daily. Maximum recommended daily dose: 20 mcg-400 mcg.
For previous therapy of high dose inhaled corticosteroids: 5 mcg-200 mcg 2 inhalations twice daily. Maximum recommended daily dose: 20 mcg-800 mcg.
Formoterol-mometasone should be administered as two inhalations twice daily every day (morning and evening) by the orally inhaled route. Shake well prior to each inhalation.
Usual Pediatric Dose of Dulera for Asthma - Maintenance:
The recommended starting dosages for formoterol-mometasone treatment are based on prior asthma therapy.
12 years of age and older:
For previous therapy of medium dose inhaled corticosteroids: 5 mcg-100 mcg 2 inhalations twice daily. Maximum recommended daily dose: 20 mcg-400 mcg.
For previous therapy of high dose inhaled corticosteroids: 5 mcg-200 mcg 2 inhalations twice daily. Maximum recommended daily dose: 20 mcg-800 mcg.
Formoterol-mometasone should be administered as two inhalations twice daily every day (morning and evening) by the orally inhaled route. Shake well prior to each inhalation.
What should I avoid?
Do not use a second form of formoterol (such as Foradil, Perforomist, or Symbicort) or use another similar long-acting inhaled bronchodilator (LABA) such as salmeterol (Advair, Serevent) or arformoterol (Brovana).
Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using Dulera.
Dulera side effects
Get emergency medical help if you have any signs of an allergic reaction to Dulera: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
sores or white patches in your mouth or throat;
wheezing, choking, or other breathing problems after using this medication;
blurred vision, eye pain, or seeing halos around lights;
changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist);
chest pain, fast or pounding heartbeats, tremors, restless feeling, seizure;
low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling;
high blood sugar (increased thirst, increased urination, hunger, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss); or
worsening asthma symptoms.
Common Dulera side effects may include:
headache;
runny or stuffy nose, sinus pain;
cough, sore throat; or
flu symptoms.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Dulera?
Tell your doctor about all your current medicines and any you start or stop using during your treatment with Dulera, especially:
nefazodone;
an antibiotic - clarithromycin, telithromycin;
antifungal medicine - itraconazole, ketoconazole, posaconazole, voriconazole;
heart medication - nicardipine, quinidine; or
antiviral medicine to treat hepatitis C or HIV/AIDS - atazanavir, boceprevir, cobicistat, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir.
This list is not complete. Other drugs may interact with Dulera, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Doxycycline
Generic Name: doxycycline (DOX i SYE kleen)
Brand Names: Acticlate, Adoxa, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Ocudox Convenience Kit, Oracea, Oraxyl, Targadox, Vibramycin
Brand Names: Acticlate, Adoxa, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Ocudox Convenience Kit, Oracea, Oraxyl, Targadox, Vibramycin
What is doxycycline?
Doxycycline is a tetracycline antibiotic that fights bacteria in the body.
Doxycycline is used to treat many different bacterial infections, such as acne, urinary tract infections, intestinal infections, eye infections, gonorrhea, chlamydia, periodontitis (gum disease), and others.
Doxycycline is also used to treat blemishes, bumps, and acne-like lesions caused by rosacea. It will not treat facial redness caused by rosacea.
Some forms of doxycycline are used to prevent malaria, to treat anthrax, or to treat infections caused by mites, ticks, or lice.
Important information
You should not take doxycycline if you are allergic to any tetracycline antibiotic.
Children younger than 8 years old should use doxycycline only in cases of severe or life-threatening conditions. This medicine can cause permanent yellowing or graying of the teeth in children.
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Using doxycycline during pregnancy could harm the unborn baby or cause permanent tooth discoloration later in the baby's life.
Before taking this medicine
You should not take this medicine if you are allergic to doxycycline or other tetracycline antibiotics such as demeclocycline, minocycline, tetracycline, or tigecycline.
To make sure doxycycline is safe for you, tell your doctor if you have:
liver disease;
kidney disease;
asthma or sulfite allergy;
a history of increased pressure inside your skull;
if you also take isotretinoin (Amnesteem, Claravis, Sotret); or
if you take seizure medicine (carbamazepine, phenobarbital, phenytoin), or a blood thinner (warfarin, Coumadin, Jantoven).
If you are using doxycycline to treat gonorrhea, your doctor may test you to make sure you do not also have syphilis, another sexually transmitted disease.
Taking this medicine during pregnancy may affect tooth and bone development in the unborn baby. Taking doxycycline during the last half of pregnancy can cause permanent tooth discoloration later in the baby's life. Tell your doctor if you are pregnant or if you become pregnant while using this medicine.
Doxycycline can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.
Doxycycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breast-feed while you are taking this medicine.
Children should not use this medicine. Doxycycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old.
Children should use doxycycline only in cases of severe or life-threatening conditions such as anthrax or Rocky Mountain spotted fever. The benefit of treating a serious condition may outweigh any risks to the child's tooth development.
How should I take doxycycline?
Take doxycycline exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take doxycycline with a full glass of water. Drink plenty of liquids while you are taking this medicine.
Most brands of doxycyline may be taken with food or milk if the medicine upsets your stomach. Different brands of doxycycline may have different instructions about taking them with or without food.
Take Oracea on an empty stomach, at least 1 hour before or 2 hours after a meal.
You may open a Doryx capsule or break up a Doryx tablet and sprinkle the medicine into a spoonful of applesauce to make swallowing easier. Swallow right away without chewing. Do not save the mixture for later use. Drink a full glass (8 ounces) of cool water right away.
Do not crush, break, or open a delayed-release capsule or tablet. Swallow the pill whole.
You may need to split the Acticlate tablet to get the correct dose. The tablet is scored so you can break it apart easily.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
If you take doxycycline to prevent malaria: Start taking the medicine 1 or 2 days before entering an area where malaria is common. Continue taking the medicine every day during your stay and for at least 4 weeks after you leave the area. Use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Doxycycline will not treat a viral infection such as the flu or a common cold.
If you need surgery, tell the surgeon ahead of time that you are using doxycycline. You may need to stop using the medicine for a short time.
Store at room temperature away from moisture and heat.
Throw away any unused medicine after the expiration date on the label has passed. Using expired doxycycline can cause damage to your kidneys.
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking doxycycline?
Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking doxycycline.
Avoid taking any other antibiotics with doxycycline unless your doctor has told you to.
Avoid exposure to sunlight or tanning beds. Doxycycline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking this medicine and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Doxycycline side effects
Get emergency medical help if you have any signs of an allergic reaction to doxycycline: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
changes in your vision;
severe stomach pain, diarrhea that is watery or bloody;
fever, swollen glands, body aches, flu symptoms, weakness;
skin rash, pale skin, easy bruising or bleeding, severe tingling, numbness, pain, muscle weakness;
upper stomach pain (may spread to your back), loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
chest pain, irregular heart rhythm, feeling short of breath;
confusion, nausea and vomiting, swelling, rapid weight gain, little or no urinating;
new or worsening cough with fever, trouble breathing;
increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common doxycycline side effects may include:
nausea, vomiting, upset stomach;
mild diarrhea;
skin rash or itching; or
vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect doxycycline?
Other drugs may interact with doxycycline, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
